Anti-Cancer Drugs
The year 2016 witnessed recordable number of US Food and Drug Administration (FDA) approvals of new pharmaceuticals, including new molecular entities (NMEs) and new Biologic License Applications (BLAs). The number was as high as 45 NMEs and BLAs in all disease states compared with 41 approved in 2014 and only 27 in 2013. Out of these 45 NMEs and BLAs entering the market last year, 16 were novel therapies for cancer. According to the Pharmaceutical Research and Manufacturers of America (PhRMA), as many as 836 drugs and vaccines are at various stages of development for cancer; these are either in clinical trials or are awaiting review by the FDA.
Of the 836 drugs and vaccines for cancer:
- 123 are for lung cancer (still the leading cause of cancer-related death in the United States)
- 106 for leukaemia
- 92 for lymphoma (including non-Hodgkin lymphoma)
- 82 for breast cancer (the leading cancer in US women)
- 58 for brain tutors
- 53 for skin cancer (including melanoma)
- Alkylating Agents
- Platinum Analogs
- Antimetabolites
- Plant Alkaloids
- Antitumor Antibiotics
- Hormonal Agents
- Differential Inducer
- Gene Targeted Drugs
- Immunomodulators
- Antiangiogenesis Drugs
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